专利名称：Method for relative quantification of nucleic
acid sequence, expression, or copy changes,using combined nuclease, ligation, andpolymerase reactions
发明人：Francis Barany,Eugene Spier,Alain Mir申请号：US15425516申请日：20170206公开号：US10338062B2公开日：20190702
专利附图：
摘要：The present invention is directed to methods for identifying the presence of
one or more target nucleotide sequences in a sample that involve a nuclease-ligationreaction. In some embodiments, the ligation products formed in the nuclease-ligationprocess of the present invention are subsequently amplified using a polymerase chainreaction. The ligated product sequences or extension products thereof are detected, andthe presence of one or more target nucleotide sequences in the sample is identifiedbased on the detection.
申请人：Cornell University
地址：Ithaca NY US
国籍：US
代理机构：Pepper Hamilton LLP
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