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METHOD FOR EXPRESSION OF SMALL ANTIVIRAL RNA MOLEC

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专利名称:METHOD FOR EXPRESSION OF SMALL

ANTIVIRAL RNA MOLECULES WITHIN A CELL

发明人:BALTIMORE, David,QIN, Xiao-Feng,LOIS-CABALLE, Carlos,Irvin S.Y. Chen,Dong SungAn

申请号:EP02761659.8申请日:20020913公开号:EP14245B1公开日:20090812

摘要:In one aspect, the invention provides methods and compositions for theexpression of small RNA molecules within a cell using a retroviral vector. The methodscan be used to express double stranded RNA complexes. Small interfering RNA (siRNA)can be expressed using the methods of the invention within a cell to interfere with a virallife cycle. In another aspect the invention provides methods for treating patients havingsuffering from infection, particularly infection with HIV.

申请人:CALIFORNIA INST OF TECHN,UNIV CALIFORNIA

地址:US,US

国籍:US,US

代理机构:Straus, Alexander

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