专利名称：COMPOUNDS AND COMPOSITIONS FOR
INHIBITING THE ACTIVITY OF SHP2
发明人：TOURE, Bakary-Barry,CHEN,
Zhuoliang,FORTANET, Jorge Garcia,JOUK,Andriana,KARKI, Rajesh,LAMARCHE, MatthewJ.,LIU, Gang,PALERMO, Mark G.,PEREZ,Lawrence Blas,SARVER, Patrick
James,SHULTZ, Michael David,YU, Bing
申请号：EP16731666.0申请日：20160615公开号：EP3310774A1公开日：20180425
摘要：in which Y1, Y2, Y3, R1, R2, R4a, R5b, R5a, R5b, R6a and R6b are defined in theSummary of the Invention; capable of inhibiting the activity of SHP2. The invention furtherprovides a process for the preparation of compounds of the invention, pharmaceuticalpreparations comprising such compounds and methods of using such compounds andcompositions in the management of diseases or disorders associated with the aberrantactivity of SHP2.
申请人：Novartis AG
地址：Lichtstrasse 35 4056 Basel CH
国籍：CH
代理机构：Strang, Andrea Josephine
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