PDE10 INHIBITORS AND RELATED COMPOSITIONS AND METH

专利名称：PDE10 INHIBITORS AND RELATED

COMPOSITIONS AND METHODS

发明人：Neil S. Cutshall,Jennifer Lynn Gage,Thomas

Neil Wheeler

申请号：US12535598申请日：20090804

公开号：US20100035872A1公开日：20100211

专利附图：

摘要：Compounds that inhibit PDE10 are disclosed that have utility in the treatment ofa variety of conditions, including (but not limited to) psychotic, anxiety, movement

disorders and/or neurological disorders such as Parkinson's disease, Huntington'sdisease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebralpalsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders,drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceuticallyacceptable salts, stereoisomers, solvates and prodrugs of the compounds are alsoprovided. Also disclosed are compositions containing a compound in combination with apharmaceutically acceptable carrier, as well as methods relating to the use thereof forinhibiting PDE10 in a warm-blooded animal in need of the same.

申请人：Neil S. Cutshall,Jennifer Lynn Gage,Thomas Neil Wheeler

地址：Snohomish WA US,Kenmore WA US,Raleigh NC US

国籍：US,US,US

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