FATTY ACID ESTERS OF LACTIC ACID SALTS AS PERMEATI

专利名称：FATTY ACID ESTERS OF LACTIC ACID SALTS

AS PERMEATION ENHANCERS

发明人：VENKATESHWARAN, Srinivasan,FIKSTAD,

David,PATEL, Sonal, R.

申请号：EP97946387.0申请日：19971029公开号：EP0942697A1公开日：19990922

摘要：Invention patent: < b > \\\"fatty acid esters of glycolic acid and its salts asreal\çadores Permeation\\\" < d >.A system for transdermal release of medicine,which enhances the release of the product, comprises a composition containing, as abooster.One or more C ~ 5 ~ C ~ 21 ~ esters of fatty acid glic\órico acid and theirsalts.These compositions are composed of a quantity hold a permeante active

pharmaceutical contained in a vehicle for increased penetration, including 0.25 to 50% byweight of acentuador of fatty acid ester at a vehicle carrying appropriate.These boostersof glic\órico acid ester of fatty acid can be used in various vehicles carriers to enhancethe transdermal release of permeantes assets,Or in free form or used in an occlusivedevice, particularly in a plaster patch in the form of a matrix or a reservoir.When used inthe form of poultice of matrix, the boosters of glic\órico acid ester of fatty acids andthe permeantes are incorporated into a biocompatible adhesive.When used as a poulticetype reservoir, the permeante and boosters of glic\órico acid ester of fatty acids areincorporated into a carrier fluid of controlled viscosity.As a gel or ointment, preferablycontaining a alcanol lower and water.In the free form the booster and the permeante

may be incorporated into an ointment, lotion, cream or similar wording.

申请人：THERATECH, INC. (a Delaware Corporation)

地址：417 Wakara Way Suite 100 Salt Lake City, Utah 84108 US

国籍：US

代理机构：Thomson, Paul Anthony

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