专利名称：MIR-193A-3P AND ASSOCIATED GENES
PREDICT TUMORIGENESIS ANDCHEMOTHERAPY OUTCOMES
发明人：JINGDE ZHU申请号：US13829903申请日：20130314
公开号：US20130310406A1公开日：20131121
摘要：The disclosure provides a correlation between the expression level of the miR-193a gene, which can be regulated by its methylation status, and both tumorigenesis ofand the resistance of a cancer cell to a pyrimidine antimetabolite (5-FU) based
chemotherapy. In addition to the methylation status and the expression of miR-193a, itsdownstream genes, such as E2F1, SRSF2, and apoptotic genes such as caspase 2, are alsoinvolved and can serve as useful markers for cancer therapy prognosis and for therapyselection.
申请人：JINGDE ZHU
地址：YUSHAN TOWN CN
国籍：CN
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