专利名称:Tissue specific adenoviral vectors发明人:Daniel R. Henderson,Eric R. Schuur申请号:US10822873申请日:20040413
公开号:US20040241857A1公开日:20041202
摘要:Host cell specific adenovirus vehicles are provided for transfecting target hostcells. By providing for transcriptional initiating regulation dependent upon transcriptionfactors that are only active in specific, limited cell types, virus replication will be restrictedto the target cells. The modified adenovirus may be used as a vehicle for introducing newgenetic capability, particularly associated with cytotoxicity for treating neoplasia.
申请人:HENDERSON DANIEL R.,SCHUUR ERIC R.
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