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SMALL MOLECULE INHIBITION OF INTRACELLULAR TRANSPO

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专利内容由知识产权出版社提供

专利名称:SMALL MOLECULE INHIBITION OF

INTRACELLULAR TRANSPORT

发明人:David B. Haslam申请号:US12645094申请日:20091222

公开号:US20100159468A1公开日:20100624

专利附图:

摘要:The present disclosure characterizes the activity of Golgicide A (GCA), as apotent, specific and reversible small molecule inhibitor of Golgi BFA resistance factor 1(GBF1) function. A mutant GBF1 gene that is resistant to GCA is also described. Methods

of using GCA and the GCA-resistant GBF1 gene are described including methods formodulating GBF1 activity for research and therapeutic purposes. Also described arecompositions incorporating a GCA-resistant GBF1.

申请人:David B. Haslam

地址:St. Louis MO US

国籍:US

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