Pharmaceutical compositions containing a 3-(amino-

专利名称：Pharmaceutical compositions containing a 3-(amino-methylene)-5- phenyl-1,4-benzodiazepin-2-one and method of use

发明人：Helmut Pieper,Gerd Kruger,Johannes

Keck,Klaus-Reinhold Noll,Joachim Kaehling

申请号：US05/532069申请日：19741212公开号：US03956492A公开日：19760511

摘要：Pharmaceutical dosage unit compositions containing as an active ingredient acompound of the formula ##SPC1##

Wherein< P>

R.sub.1 and R.sub.2, which may be identical to or different from each other, are eachhydrogen, cycloalkyl, phenyl, --A-- Y

wherein

A is alkyl of 1 to 5 carbon atoms or alkenyl of 1 to 5 carbon atoms, and

Y is furyl, dialkylamino, hydroxyl, carbalkoxy or carbamido,

Or, together with each other and the nitrogen atom to which they are attached,pyrrolidino, piperidino, hexamethyleneimino, morpholino, thiomorpholino,thiomorpholino-S-oxide or N'-alkylpiperazino,

R.sub.3 is halogen, nitro or trifluoromethyl,

R.sub.4 is hydrogen, halogen or trifluoromethyl, and

R.sub.5 is hydrogen, alkyl, cycloalkyl-methyl, alkylamino-alkyl, dialkylamino-alkyl ortrifluoromethyl-alkyl;

And a method of using the same as sedatives, tranquilizers, muscle-relaxants andanticonvulsives.

申请人：BOEHRINGER INGELHEIM GMBH

代理机构：Hammond & Littell

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