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SUBSTITUTED PYRAZOLOIMIDAZOLO BICYCLIC COMPOUNDS

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专利名称:SUBSTITUTED PYRAZOLO/IMIDAZOLO

BICYCLIC COMPOUNDS AS PDE2INHIBITORS

发明人:MORRIELLO, Gregori J.,CHANG,

Lehua,FORSTER, Ashley,CHEN, Yili,DWYER,Michael, P.,BERGER, Richard,WANG,Ming,NANDA, Kausik K.,BUNDA, JaimeL.,SHIPE, William D.

申请号:EP16815100.9申请日:20160620公开号:EP3313852A1公开日:20180502

摘要:The present invention is directed to pyrimidine carboxamide compounds offormula I which are useful as therapeutic agents for the treatment of central nervoussystem disorders associated with phosphodiesterase 2 (PDE2). The present invention alsorelates to the use of such compounds for treating neurological and psychiatric disorders,such as schizophrenia, psychosis, Parkinson's disease, Parkinson's disease dementia(PDD), or Huntington's disease, and those associated with striatal hypofunction or basalganglia dysfunction.

申请人:Merck Sharp & Dohme Corp.

地址:126 East Lincoln Avenue Rahway, NJ 07065-0907 US

国籍:US

代理机构:Jaap, David Robert

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