IMPLANT SURFACES THAT ENHANCE OSTEOINDUCTION

专利名称：IMPLANT SURFACES THAT ENHANCE

OSTEOINDUCTION

发明人：Michelle B. Gallagher,Mark E. Berg,Jennifer

M. Schneider

申请号：US16322373申请日：20170629

公开号：US20190192303A1公开日：20190627

专利附图：

摘要：Bone-contacting surfaces and free surfaces of orthopedic implants. Theimplants are additively manufactured, followed by mechanical, chemical, or mechanical

and chemical erosion. At least some of the surfaces of the implants include an

osteoinducting roughness that has micro-scale structures and nano-scale structures thatfacilitate and enhance osteoinduction and osteogenesis, as well as enhanced alkalinephosphatase, osterix, and osteocalcin expression levels along the pathway ofmesenchymal stem cell differentiation to osteoblasts.

申请人：Titan Spine, Inc.

地址：Mequon WI US

国籍：US

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