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Manumycin derivatives, process for their preparati

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专利名称:Manumycin derivatives, process for their

preparation and their use

发明人:ZEECK, AXEL, PROF. DR.,THIERICKE,

RALF,ZAHNER, HANS, PROF. DR.,DICKNEITE,GERHARD, DR.,SEDLACEK, HANS HARALD,DR.

申请号:EP881190.6申请日:19881125公开号:EP0318849A3公开日:19901219

摘要: …… …The compounds of the formula I are prepared by fermentation in thepresence of substituted benzoic acids of the general formula II …… in which… R<1> is Hor OH;… R<2> is H or OH;… R<3> is H, OH, OCH3, CH3 or NH2;… R<4> is H, OH, OCH3 orNH2,… by the strain Streptomyces parvulus DSM 40722, inhibit leucocyte elastase and canbe used as medicaments.

申请人:BEHRINGWERKE AKTIENGESELLSCHAFT

地址:Postfach 1140 35001 Marburg DE

国籍:DE

代理机构:Fischer, Hans-Jürgen, Dr.

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