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Tripeptides and methods for their production

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专利名称:Tripeptides and methods for their

production

发明人:Francis John Tinney申请号:US05/650096申请日:19760119公开号:US04022760A公开日:19770510

摘要:New tripeptides having the formula A-R.sub.1 -Tyr(benzyl)- Thr(benzyl)- R.sub.2wherein A is t-butoxycarbonyl or cyclohexylcarbonyl, R.sub.1 is Trp, His(benzyl),Cys(benzyl) or Pro and R.sub.2 is lower alkoxy, hydrazino, amino, lower alkylamino,di(lower alkyl)amino, benzylamino, allylamino, (diethoxyphosphinyl)methylamino, 2-(diethoxyphosphinyl) ethylamino or 2-[[(phenylmethyl)amino]sulfonyl] ethylamino,methods for their production, and the use of said tripeptides as luteinizing hormonereleasing factor antagonists.

申请人:PARKE, DAVIS & COMPANY

代理人:Stephen Raines,George M. Richards,David B. Ehrlinger

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