专利名称：SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINE
DERIVATIVES, PHARMACEUTICAL
COMPOSITIONS, AND METHODS OF USE ASBETA-SECRETASE INHIBITORS
发明人：Adnan M.M. Mjalli,Anitha Hari,Bapu
Gaddam,Devi Reddy Gohimukkula,DharmaRao Polisetti,Mohan Rao,Raju BoreGowda,Robert Carl Andrews,RongyuanXie,Soumya P. Sahoo,Tan Ren,WilliamKenneth Banner
申请号：US13052544申请日：20110321
公开号：US20110237570A1公开日：20110929
摘要：The present invention provides substituted imidazo[1,2-b]pyridazine derivatives,pharmaceutically acceptable salts thereof, and tautomers of any of the foregoing, wheresuch compounds inhibit β-site amyloid precursor protein-cleaving enzyme (BACE), whichmay be useful in the treatment of diseases in which BACE is involved, such as Alzheimer'sdisease. The invention also provides pharmaceutical compositions comprising any ofthese compounds and the use of any of these compounds and compositions in thetreatment of diseases, disorders, or conditions in which BACE is involved.
申请人：Adnan M.M. Mjalli,Anitha Hari,Bapu Gaddam,Devi Reddy Gohimukkula,DharmaRao Polisetti,Mohan Rao,Raju Bore Gowda,Robert Carl Andrews,Rongyuan Xie,Soumya P.
Sahoo,Tan Ren,William Kenneth Banner
地址：Oak Ridge NC US,High Point NC US,High Point NC US,Jamestown NC US,HighPoint NC US,Greensboro NC US,Oak Ridge NC US,Jamestown NC US,Greensboro NCUS,Greensboro NC US,Colfax NC US,Greensboro NC US
国籍：US,US,US,US,US,US,US,US,US,US,US,US
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